Mice were decapitated, their brains were collected and immediately submerged in ice-cold, carbogen-saturated (95% O 2 and 5% CO 2 ) artificial cerebrospinal fluid (aCSF
Pill swallowing by adults with dysphagia
The current standard operating procedure by the European Center for the Validation of Alternative Methods (ECVAM) recommends the use of MTT reduction as parameter to make prediction on the skin irritancy of substances using EpiSkin TM test method, while IL-1 endpoint is regarded as a useful adjunct to MTT assay 48
Redox regulation of immunometabolism
Ramchandani D, Berisa M, Tavarez DA, Li Z, Miele M, Bai Y
Phase 2: Remodeling (Weeks 58) Dose: 5/week Same per-injection amounts