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Discontinuation rates due to AEs: - Placebo: 4.9% - 4 mg: 4.1% - 9 mg: 6.9% - 12 mg: 11.3% The 11.3% discontinuation rate at the highest dose is a number worth watching

Tirzepatide has not yet completed a comparable cardiovascular outcomes trial, though studies are underway and early signals are promising

GLP-1 prescriptions compared to Novos 42%

It targets a different two-receptor combination than tirzepatide (glucagon instead of GIP), which gives it unique metabolic benefits, particularly for liver fat

SLU-PP-332 This mitochondrial uncoupler increases basal metabolic rate and fat oxidation without stimulant effects

The New York Times ran a piece in January on Chinese peptides as the new status drug of the tech world