Its physiological actions include stimulating glucose-dependent insulin secretion from pancreatic beta cells, suppressing glucagon release, slowing gastric emptying, and promoting satiety through central nervous system pathways
The IA used the following data sources to conduct the assessment: Approved DSRIP Project Plan Applications, PPS Quarterly Report Submissions - DY1, Q1 through DY2, Q1 and claims and non-claims data for P4R/P4P measures
PLoS ONE 3(11): e3815
19 Dei CasA.MicheliM.AldigeriR.GardiniS.Ferrari-PellegriniF.PeriniM.et al (2024)
Pancreatitis, gallbladder problems, potential thyroid concerns (theres a black box warning about thyroid C-cell tumors based on rodent studies, though this hasnt been seen in humans)
Ozempic is also approved to reduce the risk of heart attack, stroke, or death in people with type 2 diabetes and heart disease