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In rodents testis, PHGPx is localized in the interstitial cells of Leydig, in the nucleus of round spermatids, at the level of the cytoplasm and in the mitochondrial capsule of spermatozoa (25)

Because colistin is a substrate of the carnitine/organic cation transporter 2 (OCTN2, SLC22A5 ), we also considered the possibility that co-incubation with L-carnitine reduced colistin intracellular accumulation and toxicity

But individual peptides also present specific potential risks

Additionally, oral supplements can cause mild stomach discomfort or prove less effective due to inadequate intestinal absorption

Here, we report that at a late life stage, history of APAP intoxication is associated with accelerated worsening of non-spatial memory deficits, but not spatial memory performance

Currently, the diagnosis of AD dementia is based on clinical symptoms, cognition and daily functioning, and can be combined with determination of biomarker levels 5