improved mood scores (Beck depression inventory) improved general health questionnaire improved depression anxiety and stress scale
Mounjaro, a prescription medication developed by Eli Lilly, contains tirzepatide and is FDA-approved for managing type 2 diabetes in adults
Switching from Mounjaro, Ozempic, Rybelsus, or Compounded Semaglutide Switching from Mounjaro to the Wegovy pill is not the same as switching between Wegovy formulations
Ann Surg 234 : 8591 Reincke M et al
The studys methodology and findings revealed data points: Among 710 type 2 diabetes patients, 17 semaglutide users developed NAION versus only 6 non-users, despite similar baseline characteristics In the weight loss cohort of 979 patients, NAION occurred in 20 semaglutide users compared to 3 in the control group Cumulative NAION incidence over 36 months reached 8.9% for diabetic semaglutide users versus 1.8% for non-GLP-1 medications Weight loss patients showed 6.7% NAION incidence with semaglutide versus 0.8% without Manual chart review by neuro-ophthalmology specialists ensured diagnostic accuracy often lacking in larger database studies Risk persisted after controlling for known NAION risk factors including age, sex, hypertension, and sleep apnea The biological plausibility of semaglutide-induced NAION stems from multiple proposed mechanisms that researchers continue investigating
Sarcopenia 9 , 7075 (2023)
