In research, the effect of melatonin on the sensitivity of 5-FU was investigated
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It has been declared, that neurotoxic 6-hydroxydopamine (and also superoxide radical) is able to release free iron from ferritin which in turn may participate in Fenton chemistry, forming ROS and initiating lipid peroxidation (Monteiro and Winterbourn 1989)
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Nitric oxide, oxidative stress, and progression of chronic renal failure