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3.1.1.2 Non-Oral On-Demand Formulations Absorption of levodopa after oral dosing is subject to a variety of potentially interfering mechanisms including dysphagia, esophageal dysmotility, delayed gastric emptying due to gastroparesis or decreased intestinal absorption due to transport competition with dietary amino acids or decarboxylation by gut microbiota [27,28,29]

For many of the most common modern insulins, that is 28 days or 4 weeks