They also act on the appetite centers in the brain, significantly reducing hunger and what is often called food noise. The dual-action drug tirzepatide works on both GLP-1 and GIP receptors, often leading to even greater efficacy
The global prevalence of 537 million affected in the age group of 2079 years in 2021 will rise to 783 million in 2045, with the lowest increase in incidence in Europe (13%) and the highest in the African countries south of the Sahara (134%) (1)
Effects of retatrutide on body composition in people with type 2 diabetes
A 2025 radiographic study found an average 7% reduction in midfacial volume for every 10 kilograms of total weight lost, with most of the change occurring in superficial facial fat pads
Liraglutide (Victoza, Saxenda), administered once daily, has an intermediate half-life of approximately 13 hours and typically clears from the body within 3 days (about 5 half-lives) of discontinuation
Whether youre taking these medications, considering them, or simply feeling confused about all the hype, I want to open up the conversation and help make it less overwhelming, and quite frankly, shame-free
