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Wolffenbuttel, B

doi:10.5664/jcsm.6622

Global health agencies like the World Health Organization (WHO) and the United Kingdom National Institute for Health and Care Excellence (NICE) recommend that GLP-1 RAs be prescribed along with comprehensive lifestyle interventions to ensure long-term success

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Consistently, GLP-1 RA therapy is associated with higher circulating levels of PYY in humans, an appetite-suppressing hormone often co-secreted with GLP-1, and this may be partly mediated by SCFA signaling (58, 63)