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Its essential for regulating: Your sleepwake cycle Blood sugar and metabolism Inflammation and immune response Fat storage and energy use However, during menopause, reduced levels of oestrogen and progesterone can make the body more sensitive to cortisolleading to stronger and longer-lasting stress responses

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Inactivation of the APC tumor suppressor gene initiates colorectal neoplasia, and is also involved in FAP-related thyroid tumors