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Safety Profile and Reported Side Effects The most common side effects are gastrointestinal nausea, vomiting, and diarrhoea alongside a modest increase in resting heart rate

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The Epworth Sleepiness Scale (ESS) score was applied in order to estimate the clinical impact on EDS

Functional activation of muscle during exercise may improve efficiency and exercise adaptation

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Patients with diabetic macular edema, severe or proliferative diabetic retinopathy, as well as those with a history of prior retinal surgeries were excluded