GLP-1 is also involved in multiple other physiological processes including appetite, cardiovascular function, and inflammation ( Acute Inflammation is central to in-vivo responses to a wide range of challenges including viral and bacteriological infections, and to host repair processes
The net metabolic effects in humans remain under active investigation, and mechanistic claims should be understood as evolving evidence rather than established fact
Using a fresh needle each time and making sure the skin is clean before injecting can also help reduce irritation and pain
Some have been found to also protect the heart, and can benefit people at risk for a heart attack
The science behind it is pretty fascinating
Following the phase 2 results published in 2023, Eli Lilly has progressed retatrutide into phase 3 clinical development