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MOTS-c Primary focus: Mitochondrial metabolism Insulin sensitivity Metabolic aging in women MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is encoded in mitochondrial DNA not the nuclear genome and functions as a mitochondrial-derived peptide that communicates metabolic stress signals systemically

Cell (1997) 89(5):74754.10.1016/S0092-8674(00)80257-3 34 YoshimuraNMurakiSOkaHKawaguchiHNakamuraKAkuneT

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10 , 46 Moreover, the expression of GLP1 level was found to be significantly reduced in the peritoneal fluid of patients with endometriosis compared to controls

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