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As retatrutide has not yet received marketing authorisation from the MHRA or EMA, it is only available within regulated clinical trials in the UK
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13-16 weeks : After assessment, your doctor will escalate the dosage to 8 mg once weekly for the next 4 weeks 17-21 weeks : If your body tolerates 8 mg for 4 weeks, your doctor will increase the dose to 12 mg once weekly onwards
For women who could become pregnant, it's advised to stop taking Rybelsus at least two months before a planned pregnancy because the medication stays in your system for some time, and there isn't enough human data to confirm its safety during pregnancy
Nature 455, 894902
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