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In contrast, a 54-week trial of liraglutide did not show significant motor improvement (MDS-UPDRS III), but daily living activities (MDS-UPDRS II) improved significantly, suggesting functional gains without direct motor benefit [57]

Diabetes Care 41:389390

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Pair feeding experiments indicate Vutiglabridin exerts an additional effect beyond food intake suppression, consistent with its distinct metabolic action on fat mass