In one study, participants regained two-thirds of their previous weight loss within the year after stopping the medication
Y.McLennanT.CzieselskyK.HerbisonA
Rates of treatment discontinuationmost commonly from gastrointestinal symptomswere higher, at 6 to 10 percent, depending on the dose, for those who received the pill, compared with a rate of 4 percent for those who received the placebo
This could be because those with obesity had a more difficult time obtaining insurance benefits for these expensive medications
A longstanding unmet need in the care of T2DM and obesity has been to identify therapies that deliver effective glycemic control and clinically meaningful weight loss without increasing cardiovascular risk or severe hypoglycemia
Seek immediate medical attention (999 or A&E) for chest pain, seizures, loss of consciousness, or severe dehydration symptoms