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In that study, BNP increased with the progressively increased severity of mitral valve disease and CHF

While bowel habits are highly individual, general indicators of constipation include: Infrequent Bowel Movements: Typically, fewer than three bowel movements per week

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The ADA's 2024 Standards of Care explicitly recommend considering GLP-1 RAs for overweight or obese adults with type 2 diabetes as preferred second-line therapy after metformin 5

References: Raun K , Hansen B , Johansen N , et al