Chang W, Zhu F, Zheng H, Zhou Z, Miao P, Zhao L, Mao Z
GLP-1 receptor agonists directly activate GLP-1 receptors and are FDA-approved for both glycemic control and weight management at specific doses, while DPP-4 inhibitors prevent breakdown of endogenous GLP-1, are used only for glycemic control, and are weight-neutral
Bhatt DL, Szarek M, Pitt B, Cannon CP, Leiter LA, McGuire DK, Lewis JB, Riddle MC, Inzucchi SE, Kosiborod MN, Cherney DZI, Dwyer JP, Scirica BM, Bailey CJ, Diaz R, Ray KK, Udell JA, Lopes RD, Lapuerta P, Steg PG
Both cases reduce to the same principle the guts tolerance is built gradually and is not permanent
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