While this effect appears to be related to the magnitude and rapidity of glucose lowering rather than a direct effect of the medication itself, patients with a history of diabetic retinopathy should undergo careful ophthalmologic evaluation before and during treatment, and the potential risks should be weighed against the expected benefits of improved glycemic control
World J Gastroenterol 23:4658488 Farges M, Balcerzak D, Fisher B, Attaix D, Bchet D, Ferrara M, Baracos V (2002) Increased muscle proteolysis after local trauma mainly reflects macrophage-associated lysosomal proteolysis
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