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Life Sci 145

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One study that focused on bone mineral density (BMD) and bone mineral content (BMC) in 59 African American and 59 white girls, aged 710 years, found that higher plasma IGF-1 concentrations were correlated with better BMD/BMC in younger age too

Ethanol metabolism, CYP2E1 induction, compromised antioxidant defenses, mitochondrial injury, activation of Kupffer and stellate cells, hypoxia, and iron overload can all contribute to the alcohol-induced oxidative environment