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Lack of DNA methylation in Schistosoma mansoni

SCI is usually accompanied by the destruction of intestinal ecology through mechanisms associated with disruption of signals from higher control center, autonomic nerve dysfunction, intestinal barrier permeability change, mesenteric lymph node immune regulation, and long-term use of antibiotics (Cervi et al., 2014

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EspG and VirA, along with other pathogenicity factors, are encoded within horizontally transferred genomic islands that encode additional proteins enabling pathogenicity 23,24,25

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