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Levothyroxine dosing is influenced by body weight, with typical maintenance doses ranging from 1.6-1.8 mcg/kg/day based on ideal or lean body weight (using actual body weight in obesity may lead to overreplacement)

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The gap between what gut inflammation requires and what standard treatment provides comes down to three mechanisms: epithelial tight junction repair, localized anti-inflammatory signaling, and microbial translocation prevention

J., Sharma, R., Ma, Q., Rosales-Corral, S