Patients with type 2 diabetes, prediabetes, or those taking antidiabetic medications should inform their provider before adding berberine to a GLP-1 regimen
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Neurogenesis, synaptic plasticity, and metabolic support GLP-1R stimulation promotes hippocampal neurogenesis and enhances synaptic plasticity, partly through brain-derived neurotrophic factor and modulation of glutamatergic signalling
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These are some of the main situations in which it is advisable to avoid L-carnitine supplementation or to use it only under supervision
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