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Funding This study were funded by the Xingyao South Lake Leading Talent Plan-Team Project (2022-XYNHCXTD-001)

The receptors retatrutide hits are GIP, GLP-1, and glucagon (GCGR), each at different potency

We employed two different PCa cell lines (DU-145 and 22Rv1), that were xenografted in Nu/MRI nude mice by subcutaneous injection

Suppositories provide very similar results to IV methods of administration since the ingredients in the suppository are absorbed by the wall of the rectum and carried straight into the systemic circulation (circumventing the entero-hepatic portal system where ingredients are broken down)

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Danial, J