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These include phentermine and topiramate

Future directions include the design and synthesis of novel compounds that can mitigate these side effects while maintaining or enhancing efficacy

As the field moves toward oral small molecules such as Elecoglipron, balancing innovation with rigorous safety science will remain central to the future of GLP-1 therapeutics

Muscle Mass Reduction Studies indicate that up to 40% of weight loss on some GLP-1 medications can actually be lean muscle rather than fat tissue

Inflammation also changes what cholesterol does

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