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It plays a role in protecting cells from oxidative stress, recycling other antioxidants, and supporting normal liver detoxification pathways

BV-2 cells were seeded in 24-well plates overnight at a density of 2 10 5 cells/well

Astrocytes in motor neuron diseases

doi: 10.1021/acs.jafc.2c06162

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Impaired FAD-dependent enzyme activity is also detrimental to bloodbrain barrier (BBB) integrity, leading to downregulation of tight-junction proteins such as claudin-5 and occluding, increased permeability, and enhanced peripheral immune infiltration