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Recent clinical data suggests they are well-tolerated , but they should only be used under medical supervision

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A case report published in Cureus described a biphasic anaphylactic reaction occurring 20 minutes after tirzepatide injection, with diffuse urticaria, throat swelling, shortness of breath, and wheezing

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While severe complications are uncommon, patients should contact their prescribing provider if they believe they have taken an incorrect dose