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The AMG 133 murine surrogate stimulates cAMP production in CHO-K1 cells expressing mouse GLP-1R with EC 50 values of 90.6 pM (Extended Data Fig

Alternative medications, dose adjustments, or additional supportive therapies may be available

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In simple terms, it mimics two natural gut hormones that help control blood sugar, slow digestion, and reduce appetite

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Coffee and the immune system