glp-1 metabolism receptor signalling promotes β-cell glucose via mTOR-dependent HIF-1α activation GLP-1 receptor agonists and myocardial

[DOI] [PubMed] [Google Scholar] 121.Kendall DM, Riddle MC, Rosenstock J, et al

The authors concluded: The use of GLP-1 agonists should be considered in T1DM patients who are overweight or obese and not at glycemic goals despite aggressive insulin therapy. After conducting clinical trials with a GLP-1 agonist, Novo Nordisk decided not to pursue FDA approval for treating type 1 diabetes

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This extended duration made practical treatment possible

& Driver, J

Articles pertinent to the aim of the review were selected based on the relevance of the title and abstract in the topic by four authors (R.M.R., E.M., L.C., and C.V.) and then were critically evaluated by all authors