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One critical warning

When to pause or reverse the taper Red flags that should pause your taper include weight gain exceeding 3% of your lowest weight, significant increase in hunger that interferes with daily functioning, worsening metabolic markers such as rising blood sugar, blood pressure, or lipid levels, return of binge eating patterns or loss-of-control eating episodes, and significant emotional distress related to appetite changes

for longer storage, aliquot and freeze at -20 C or below

Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction

Kommu S, Whitfiedl P (2024): Semaglutide

Ghrelin (the hunger hormone) rises and stays elevated