Sources: Neelakantan et al., Biochem Pharmacol 2018 | Dimet-Wiley et al., Sci Rep 2024 Security Profile & Chemical Identity Molecular specifications and preclinical safety data 5-Amino-1MQ Chemical Identity A small molecule derived from quinolinium salts, developed at the University of Texas (2017) 5-Amino-1MQ Tolerance & Status Safety data from preclinical studies (DIO mouse model) Published Preclinical Data 3 key studies published in Biochemical Pharmacology and Scientific Reports 35% Reduction of white adipose tissue in 11 days (20 mg/kg, 3 times/day) Physical Effects (11 days) + 40 % Improvement of grip strength in aged mice (22-24 months) Strength & Performance (aged mice) microbiome The combination of 5-Amino-1MQ + caloric restriction establishes a distinct gut microbial profile Protocol & Results Important Notice Search Only Not intended for human consumption
Mounjaro is a new weight loss drug authorised for weight loss and management in the UK
Lyophilized retatrutide looks like a white to off-white powder or a small disc at the bottom of the vial
These effects contribute to the healing and regeneration of damaged tissues, which can lead to pain relief and improved function
Clinical trials of FDA-approved semaglutide and tirzepatide show average weight loss of 1521% of total body weight, far beyond what lifestyle changes alone typically achieve (individual results vary and are not guaranteed)
Natural history, predictors and outcomes of depression after stroke: systematic review and meta-analysis