Additionally, its ability to improve insulin sensitivity and regulate adipose tissue inflammation makes it an attractive candidate for managing metabolic disorders beyond diabetes, such as non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome
the direct winner is now being tested
SURPASS-2: The Only Head-to-Head Trial The SURPASS-2 trial (NEJM, 2021) is the most important study in this comparison because it directly tested tirzepatide against semaglutide in 1,879 patients with type 2 diabetes over 40 weeks
Records documenting symptoms, diagnosis, treatment history, and the timing of medication use can help establish whether complications developed after exposure to semaglutide or tirzepatide medications
Cholesterol levels get better
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