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[39] reported that SRT2140, an Sirt1 agonist, could attenuate CUMS-induced depressive-like behaviors via shifting microglial polarization toward the M2 phenotype
Because of this, clinical settings often relied exclusively on intravenous (IV) glutathione or precursor amino acids to raise intracellular levels
Results tend to be subtle, appearing over 8 to 12 weeks of consistent use
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