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Guo, S., Garaj, S., Bianco, A

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This imbalance is hypothesised to be the key driver of its superior efficacy

Comorbidities Among 138 patients with documented comorbidity data, the most frequent conditions were obesity/high BMI in 34 (24.6%), T2DM in 23 (16.7%), gallstones in 27 (19.6%), and alcohol use in 27 (19.6%), with nine patients (6.5%) having both obesity and T2DM

The concern with PPIs on tirzepatide applies primarily to patients starting acid suppression for new-onset reflux caused by the medication

Growth hormone peptides: Can cause water retention, joint pain, carpal tunnel symptoms, insulin resistance (with long-term high-dose use), increased hunger (especially GHRP-6, GHRP-2)