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Thus, elevated levels of some blood biomarkers such as VEGF underline the frequent occurrence, in long COVID, of endothelial vasculitis (139, 140), dysregulated blood coagulation, with fibrin amyloid microclots and platelet pathology (141), vascular damage, repair and remodeling (142), thromboinflammation and dysregulation of the complement cascade (143)

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Further studies in aging animals will be needed to confirm LASSSs effectiveness and safety in vivo