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PMID: 41490200

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These functions include the synthesis of neurotransmitters, myelin sheath production, nerve regeneration after injury, and the buildup of powerful antioxidants such as glutathione, etc

A recent effort to systematically uncover the scope of 20S proteasome substrates, adopted a distinctive approach by preconditioning HeLa nuclear-rich cellular extracts at 95 C before subjecting them to degradation by purified 20S proteasomes (Myers et al, 2018)