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Fatigue may result from reduced caloric intake due to appetite suppression, gastrointestinal side effects affecting nutrient absorption, dehydration, blood glucose fluctuations, and the body's metabolic adjustment period during weight loss

First, inhibition of the Xc system has been shown to disrupt GSH and GPX4 synthesis by inhibiting cysteine uptake, lowering the activity of antioxidant products and increasing the expression of lipid peroxides, eventually leading to ferroptosis [22, 23]

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Caloric restriction, ketogenic diet, and intermittent fasting are among the dietary interventions predominantly employed in cancer therapy research

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AstraZeneca today announced that baxdrostat (2 mg daily, added to standard therapy) achieved its primary endpoint in a 12-week, 24-hour ambulatory blood pressure study in patients whose hypertension had failed to respond adequately