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Because the arithmetic mean cost is the statistical methodology that estimated the highest cost for the service, we proposed to use this cost to determine the New Technology APC placement

Its buyer beware basically, Wilcox said

This is known as metabolic adaptation

Mitigating Cardiovascular Risk in Type 2 Diabetes With Antidiabetes Drugs: A Review of Principal Cardiovascular Outcome Results of EMPA-REG OUTCOME, LEADER, and SUSTAIN-6 Trials

In the case of multiple tests, false discovery rate control using the Benjamini and Hochberg procedure 108 implemented in the p.adjust function of R was used