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Cells were plated in black 96-well plates at a density of 2 10 4 cells/well and cultured for 24 h

The transmembrane helices: Like any other G-protein coupled receptor, this protein has seven transmembrane helices (TM1-7) with surface exposed hydrophobic amino acids in the membrane region (see Figure 3b)

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Obesity is a major driver of US health care costs, totaling almost $173 billion annually, according to the CDC in 2024

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