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doi: 10.1099/00221287-148-2-433 136 RubinD

Some limitations of this study should be mentioned

Additionally, the cyclic trisulfide structure of LASSS, as opposed to the linear trisulfides such as GSSSG and cysteine trisulfide (Cys-SSS-Cys), could guarantee the unique reactivity of LASSS (see again Figure 1a for chemical structures)

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Patients who already qualify for GLP-1 therapy and would like additional support Individuals with suboptimal B12 levels or risk of deficiency Those who prefer combining metabolic and micronutrient therapy Patients fully committed to close medical oversight and follow-up However, its not recommended if you have contraindications to GLP-1 agents, are pregnant, breastfeeding, have uncontrolled GI disease, or cannot adhere to monitoring and follow-up