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Preparation Gather everything before you start

Importantly, GLUD1 inhibition through MLipRIR-NPs treatment has been shown to facilitate dendritic cell maturation, a process essential for antigen presentation and immune cell activation [206]

Participants received once-weekly semaglutide (initiated at 0.25 mg and gradually escalated to 2.0 mg) for 12 weeks, along with lifestyle intervention

Experiment with different injection days and times over several weeks to identify your personal optimal schedule