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DAY 4: SAN PEDRO DE ATACAMA LAGUNAS BLANCA, VERDE, COLORADA PUEBLO VILLA MAR At 6:30 in the morning, the journey to Salar de Uyuni (located in Bolivia) will kick off in San Pedro de Atacama

References References Selective and membranepermeable small molecule inhibitors of NNMT Roles of Nicotinamide NMethyltransferase in Obesity and Type 2 Diabetes Nicotinamide Nmethyltransferase inhibition mimics and boosts exercisemediated improvements in muscle function in aged mice Reduced calorie diet combined with NNMT inhibition establishes a healthier gut microbiome in obese mice Kraus et al

Because autoimmune conditions can prevent proper absorption of B12, these patients are at increased risk of deficiency

Contraindications include polycythemia vera, Leber optic neuropathy, and cobalt allergy

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However, individuals following plant-based diets should be particularly vigilant, as dietary B12 is predominantly found in meat, fish, dairy, and eggs