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Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old

had taken, within 3 months before visit 2, medications (prescribed or over-the-counter) or alternative remedies that promote weight loss Examples included, but were not limited to Saxenda (liraglutide 3.0 mg) Xenical/Alli (orlistat) Meridia (sibutramine) Acutrim (phenylpropanolamine) Sanorex (mazindol) Apidex (phentermine) BELVIQ (lorcaserin) Bontril (phendimetrazine) Qsymia (phentermine/topiramate combination) Contrave (naltrexone/bupropion) Note: use of metformin, or any other glucose-lowering medication, whether prescribed for polycystic ovarian syndrome or diabetes prevention, was not permitted

A paradoxical enrichment of both saturated (e.g., C16:0, C18:0) and polyunsaturated fatty acids (e.g., C18:1, C18:2, C18:3) was observed

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