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Oxidative stress and exposure to neurotoxins may also induce conformational changes in alpha-synuclein, promoting its aggregation into toxic forms

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Beyond transcriptional priming, this phase also orchestrates NLRP3 post-translational modifications (PTMs), including phosphorylation, ubiquitination, and SUMOylation, which play an important role in NLRP3 activation (Xu et al., 2022)

10.1016/s0031-9422(00)00103-5 11 ChoiS

PubMed Randomized trialSemaglutide evidence2021 Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance Used for maintenance, discontinuation, and weight-regain discussions after semaglutide response

J., Kwan, J