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The constitutive (calcium-dependent) isoforms, neuronal NOS (nNOS or bNOS) and endothelial NOS (eNOS), produce small amounts of NO which act as a neurotransmittor and vasodilator, respectively [84]

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15 It is not our intention to advocate the use of AOM, in particular GLP-1 RA, for every patient with obesity

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That changed in 2017, when researchers confirmed the presence of Epitalon in native pineal gland extracts, a discovery that validated its endogenous origin and helped explain its overlap with, but also differences from, Epithalamin [7]

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