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Upon binding to GLP-1, GLP-1R activates intracellular signaling pathways, such as cyclic adenosine monophosphate (cAMP) and protein kinase A (PKA), which mediate its physiological effects

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In the GLP1-RA group, cumulative incidence estimates for live births, pregnancy losses and pregnancy terminations were 59%, 23% and 18%, respectively (figure 1)

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