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In order to reduce hydrolysis and/or degradation of the therapeutic agent during sterilization, the buffer pH is designed to maintain pH of the formulation or composition in the 7-8 range during the process of sterilization

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They may also order diagnostic tests to rule out other conditions: Imaging techniques like endoscopy, ultrasound, or computed tomography (CT) are used to identify any obstructions in the gastrointestinal tract or indications of different digestive diseases

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