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The remodeling signal is maintained but exposure eases, which also stretches vial supply

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Proc Natl Acad Sci U S A (1994) 91(15):73359.10.1073/pnas.91.15.7335 146 LorenzURavichandranKSPeiDWalshCTBurakoffSJNeelBG

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However, in human systems the outcome of boosting NAD+ is complex and likely involves numerous pathways, from enhanced activity of sirtuins (implicated in longevity and metabolic control) to improved DNA damage repair, all of which are areas of ongoing investigation