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Ingredient Amount % RI Creatine monohydrate 5000 mg L-carnitine (as acetyl-L-carnitine hydrochloride) 2000 mg

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Estimation of biochemical parameters The Table 3 shows the increased level of Cholesterol, TG and LDL in the HCD rats as compared with the NC, whereas HDL was significantly reduced

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The results showed that higher levels of ROS were observed upon treatment of chondrocytes and chondral OA with IL-1