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11.3 Geopolitical Exposure in API and Starting Material Sourcing Unlike small-molecule drugs, biologics do not have an API in the traditional sense (the protein is manufactured, not sourced)

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and After at least four weeks administering a 15 mg once weekly SEQ ID NO:2 dose, administer a once weekly a SEQ ID NO:2 dose selected from the group consisting of 20mg and 25 mg

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Lindicazione terapeutica da parte dellEMA (European Medicines Agency) comprende gli adulti con BMI 30 kg/m (obesit) o con BMI 27 kg/m (sovrappeso) in presenza di comorbidit associate al peso corporeo, quali ipertensione arteriosa, dislipidemia o diabete di tipo 2